Presentation of the KidneySim Project"."
"; $str .= par("NB: This is an old prototype site. It is currently (2007-2008) being reworked into a 3D-virtual kidney interface at the University of Melbourne and the Victoria Partnership for Advanced Computing. In that resource, the legacy models are being translated into markup languages (esp. CellML) and rendered accessible through a KidneyGrid Portal.
"); $str .= par("In the context of the International Physiome project, this site is an aspect of the \"Kidney Physiome\". We present here an early (2003) prototype for a model repository, based on a Java applet for interactive presentation of simulation results."); $str .= par('This is applied, as an example, to one of our hypothesis-based models of kidney function. It includes an introduction to one of our recent models of the kidney medulla. In particular, we present simulations illustrating the possible role of inner medullary metabolic osmole production in the urine concentrating mechanism.'); $str .= par("Of course, modeling and bench-work go hand-in-hand, and even more so for the kidney than for many other systems, given the difficulties of investigating the kidney's many functions without at the same time compromising its integrity. This complementarity is explicitly recognized in the physiome concept by the stated objectives of developing public, interactive databases as well as modelling sites. As a companion to modelling studies such as the one presented in this website, we have developed the Quantitative Kidney DataBase, or QKDB, with the purpose of furnishing a unified resource containing relevant data on permeabilities, anatomy, micropuncture results, and other such data."); $str .= par("Your comments and suggestions are welcome. Please send them to Randy Thomas (srthomas@ibisc.univ-evry.fr)."); $page_content = $ma.$str; // echo main_page($page_content,"home"); toppage("KSim Home",$page_content); endpage(); ?>