KSim
A Kidney Modeling Demo:
The Urine Concentrating Mechanism
 
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KSim - BIBLIOGRAPHY


This is not an exhaustive bibliography, just a list of the few references cited in this website. For a complete reference list up to 1992 and a detailed account of the development of medullary models, see:

Stephenson, JL. 1992. Urinary concentration and dilution : models. IN: "Handbook of Physiology - Renal Physiology", sect.8, vol.2, ch.30, 1349-1408.


  1. Chon, KH, Holstein-Rathlou, NH, Marsh, DJ. Nonlinear analysis of renal autoregulation in rats using principal dynamic modes. Ann Biomed Eng. 27(1), 23-31, 1999
  2. Edwards, A, Pallone, TL. A multiunit model of solute and water removal by inner medullary vasa-recta. American Journal of Physiology - Heart & Circulatory Physiology. 43(4), H1202-H1210, 1998
  3. Hargitay, B, Kuhn, W. 1951. Das Multiplikationsprinzip als Grundlage der Harnkonzentrierung in der Niere. Z. Elektrochem. 55, 539-558
  4. Hervy, S. and S. R. Thomas (2003). "Inner medullary lactate production and urine-concentrating mechanism: a flat medullary model." Am J Physiol Renal Physiol 284(1): F65-81.
  5. Holstein-Rathlou, NH, Marsh, DJ. A dynamic model of renal blood flow autoregulation. Bull Math Biol. 56(3), 411-29, 1994
  6. Jamison, RL, Kriz, W. 1982. Urinary concentrating mechanism: structure and function. New York : Oxford university Press
  7. Jen, JF, Stephenson, JL. Externally driven countercurrent multiplication in a mathematical model of the urinary concentrating mechanism of the renal inner medulla. Bulletin of Mathematical Biology. 56, 491-514,1994
  8. Knepper, M. A., G. M. Saidel, V. C. Hascall and T. Dwyer, "Concentration of solutes in the renal inner medulla: interstitial hyaluronan as a mechano-osmotic transducer." Am J Physiol Renal Physiol 284(3): F433-446. 2003
  9. Kokko, JP, Rector, F. 1972. Countercurrent multiplication system without active transport in inner medulla. Kidney Int. 2 ,214-233
  10. Kuhn, W, Ramel, A. Aktiver Salztransport als möglicher Einzeleffekt bei der Harnkonzentrierung in der Niere. Helvetica Chimica Acta. 42, 628-660. 1959
  11. Layton, A. T., T. L. Pannabecker, W. H. Dantzler and H. E. Layton (2004). "Two modes for concentrating urine in rat inner medulla." Am J Physiol Renal Physiol.
  12. Lemley, KV, Kriz, W. : The histotopography of the urinary concentrating process. Kidney International. 31,538-548,1987
  13. Moore, LC, Marsh, DJ. 1980.How descending limb of Henle's loop permeability affects hypertonic urine formation. American Journal of Physiology Renal 239 F57-F71
  14. Niesel, W, Röskenbleck, H. Möglichkeiten der Konzentrierung von Stoffen in biologischen Gegenstromsystemen. Pflügers Arch. 276, 555-567. 1963
  15. Pallone, TL. Renal vasa-recta - passive filters or active participants. News in Physiological Sciences. 11, 191-192, 1996
  16. Pannabecker, T. L., D. E. Abbott and W. H. Dantzler (2004). "Three-dimensional functional reconstruction of inner medullary thin limbs of Henle's loop." Am J Physiol Renal Physiol 286(1): F38-45.
  17. Röskenbleck, H, Niesel, W. Gekoppelte Gegenstromsystemen als Modell der konzentrierenden Niere. Pflügers Arch. 277, 316-324. 1963
  18. Ruiz-Guinazu, A., G. Pehling, C. Rumrich and K. J. Ullrich (1961). "Glucose- und Milchsäurekonzentration an der Spitze des vasculären Gegenstromsystems im Nierenmark." Pflügers Archives 274: 311-317.
  19. Stephenson, JL. 1972. Concentration of urine in a central core model of the renal counter flow system. Kidney Int. 2 ,85-94
  20. Stephenson, JL, Tewarson, RP, Mejia, R. 1974. Quantitative analysis of mass and energy balance in non-ideal models of the renal counterflow system. Proceedings of the National Academy of Sciences USA. 71, 1618-1622
  21. Tewarson, RP, Stephenson, JL, Garcia, M, Zhang, Y. 1985. On the solution of equations for renal counterflow models. Comp.Bol.Med. 15(5), 287-295
  22. Thomas, SR. Effect of varying salt and urea permeabilities along descending limbs of Henle in a model of the renal medullary urine concentrating mechanism. Bulletin of Mathematical Biology. 53. (6). 825-843. 1991
  23. Thomas, SR. Cycles and separations in a model of the renal medulla. American Journal of Physiology - Renal 275: F671-F690,1998
  24. Thomas, S. R. (2000). "Inner medullary lactate production and accumulation: A vasa recta model." American Journal of Physiology Renal 279: F468-F481.
  25. Wang, X, Thomas, SR., A.S. Wexler. Outer medullary anatomy and the urine concentrating mechanism. American Journal of Physiology - Renal 274: F413-F424. 1998
  26. Wexler, AS, Kalaba, RE, Marsh, DJ. Three-dimensional anatomy and renal concentrating mechanism. I. Modeling results. American Journal of Physiology Renal 260: F368-F383,1991


 

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